- Metals are not altered by radiation sterilization because all the energy is dissipated, with no risk of activation.
(Ref: Manual on Radiation Sterilization of Medical and Biological Materials, Technical Reports Series No. 149, p.182, IAEA, Vienna, 1973).
More information - Metals do not adsorb ethylene oxide (Ref: Sterilisation of Biomaterials and Medical Devices, edited by Sophie Lerouge and Anne Simmons, WP Woodhead Publishing, 2012).
Compatibility Materials
Materials | Ionizing Radiation | Ethylene Oxide | |
---|---|---|---|
Compatibility related to absorption | Compatibility related to process conditions | ||
Metals | ![]() Possible shielding effect in beta | ![]() | ![]() |
Glass | Discoloration | ![]() | ![]() |
Ceramics | ![]() | ![]() Watch out for porosity level | ![]() |
Polymers | ![]() ![]() Depending on their structure* | ![]() | ![]() ![]() Depending on their structure* |
Biopolymers | Literature available upon request | ![]() | ![]() |
- Glass becomes discolored under radiation, even at low doses (a few kilograys).
- Glass retains only very small amounts of ethylene oxide (Ref: Sterilisation of Biomaterials and Medical Devices, edited by Sophie Lerouge and Anne Simmons, WP Woodhead Publishing, 2012).

- Compatibility related to absorption (beware of porosity level)
- Compatibility related to process conditions